In 1959, nine experienced cross country skiers were trapped in a snowstorm and decided to set camp and sleep it out.

What on earth would frighten them so bad they would tear apart their tents from the inside and run for their lives in minus 30 degree temps in their underwear?

This is an excerpt from Dr. Albert Hofmann's journal when he his first experimented with LSD several years after discovering it in 1938. During this experiment, he ingested 250 µg of the substance (a single hit today is about 25 µg) and proceeded to have the grandfather of all bad trips.

You can read at the beginning of his journal entry, he was so tweaked, he couldn't finish writing until he came down.

After spending several hours terrified that his body had been possessed by a demon, that his next door neighbor was a witch, and that his furniture was threatening him, Dr. Hofmann feared he had become completely insane. Stop looking at me, chair!